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Table 1 Overview of various KF methods and their corresponding settings

From: Metabolically active tumour volume segmentation from dynamic [18F]FLT PET studies in non-small cell lung cancer

KF version KC Description Undetected lesions
1 H’smith Original KF algorithm 13
2 H’smith Temporal smoothing was added 11
3 H’smith Frame times of the scan data adjusted 2
4 H’smith Liver KC reclassified as tumour KC, classification of 9- to 60-min p.i. 4
5 H’smith Liver KC reclassified as tumour KC, classification of 20- to 60-min p.i. 2
6 H’smith Liver KC omitted 6
7 H’smith Liver and vertebrae KS omitted 1
8 VUmc Original KF algorithm 10
9 VUmc Liver KC reclassified as tumour KC, temporal smoothing, classification of 15- to 60-min p.i. 2
  1. Only the results of the original KF and the eight most successful adaptations are provided. KC, kinetic class; KF, kinetic filtering; p.i., post injection.