Table 1 Overview of various KF methods and their corresponding settings

1

H’smith

Original KF algorithm

13

2

H’smith

Temporal smoothing was added

11

3

H’smith

Frame times of the scan data adjusted

2

4

H’smith

Liver KC reclassified as tumour KC, classification of 9- to 60-min p.i.

4

5

H’smith

Liver KC reclassified as tumour KC, classification of 20- to 60-min p.i.

2

6

H’smith

Liver KC omitted

6

7

H’smith

Liver and vertebrae KS omitted

1

8

VUmc

Original KF algorithm

10

9

VUmc

Liver KC reclassified as tumour KC, temporal smoothing, classification of 15- to 60-min p.i.

2