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Table 1 Radiopharmacokinetic parameters of 64 Cu-MM-302

From: Whole-body organ-level and kidney micro-dosimetric evaluations of 64Cu-loaded HER2/ErbB2-targeted liposomal doxorubicin (64Cu-MM-302) in rodents and primates

Parameter Blood
t 1/2 (h) 6.81 ± 0.58
T max (h) 1.00 ± 0.00
C max (%ID/g) 35.40 ± 1.86
CL (mL/h) 0.29 ± 0.01
V ss (mL) 2.96 ± 0.18
AUC(0−∞) (%ID/g*h) 347.90 ± 5.63
MRT(0−∞) (h) 10.31 ± 0.77
  1. Abbreviations: t 1/2 effective radioactive half-life, T max time to reach maximum concentration, C max maximum concentration, CL clearance rate, V ss apparent volume of distribution at steady state, AUC (0−∞) area under the time-activity curve from 0 h to infinity, MRT mean residence time.