Skip to main content
EJNMMI Research

Table 1 Radiopharmacokinetic parameters of 64 Cu-MM-302

From: Whole-body organ-level and kidney micro-dosimetric evaluations of 64Cu-loaded HER2/ErbB2-targeted liposomal doxorubicin (64Cu-MM-302) in rodents and primates

Parameter

Blood

t 1/2 (h)

6.81 ± 0.58

T max (h)

1.00 ± 0.00

C max (%ID/g)

35.40 ± 1.86

CL (mL/h)

0.29 ± 0.01

V ss (mL)

2.96 ± 0.18

AUC(0−∞) (%ID/g*h)

347.90 ± 5.63

MRT(0−∞) (h)

10.31 ± 0.77

  1. Abbreviations: t 1/2 effective radioactive half-life, T max time to reach maximum concentration, C max maximum concentration, CL clearance rate, V ss apparent volume of distribution at steady state, AUC (0−∞) area under the time-activity curve from 0 h to infinity, MRT mean residence time.
Back to article page