biodistribution of [
F]FDG-6-P and [
F]FDG. (a) Representative optical image confirming the presence of BL catheter-associated S. aureus on the day of the nanoScan PET-CT scan. (b) Whole body biodistributions from nanoPET-CT scans of mice with sc implanted catheters inoculated with or without S. aureus 1 h after ip injection of approximately 10 MBq [18F]FDG or [18F]FDG-6-P; catheters are shown with arrows. SUVs were calculated from 3D ROIs drawn for each mouse from the whole-body nanoScan PET-CT images for (c) infected ([18F]FDG n = 3; [18F]FDG-6-P n = 3) and (d) uninfected mice ([18F]FDG n = 3; [18F]FDG-6-P n = 2. Black circle, [18F]FDG; black square, [18F]FDG-6-P). Bars on graph show median. BAT, brown adipose tissue.