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Figure 3 | EJNMMI Research

Figure 3

From: Neurotensin receptors in pancreatic ductal carcinomas

Figure 3

Autoradiography of NT-R and competition by SR48692. NT-R autoradiography of PanIN 3 (A-D) and of an adenocarcinoma (E-H) with neurotensin and the type 1 NT-R-selective SR48692 as displacer. (A), (E) Hematoxylin-eosin-stained sections (bars = 0.1 mm). (B), (F) Autoradiograms showing total binding of 125I-[Tyr3]-neurotensin. (C), (G) Autoradiograms showing non-specific binding (in the presence of 100 nM neurotensin). (D), (H) Autoradiograms showing full displacement of 125I-[Tyr3]-neurotensin binding in the presence of 1,000 nM SR48692. The detected NT-R are therefore the type 1 NT-R.

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