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Table 4 Human in relation to mouse PET with [ 11 C]PiB

From: FIBT versus florbetaben and PiB: a preclinical comparison study with amyloid-PET in transgenic mice

 

Human

Mouse

AD

2.01 ± 0.29

2.08 ± 0.24

Controls

1.22 ± 0.12

0.99 ± 0.06

AD/ctl

1.65 ± 0.41

2.11 ± 0.24

  1. Global cortex/cerebellum ratio (expressed as SUVR) in the human AD group (N = 20) and the HC group (N = 15) vs. four APP/PS1 tg mice and three control mice.