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Table 3 Mean PET ratios (SUVR ± SD) within the four APP/PS1 tg mice and the three control mice (C57BL6/J)

From: FIBT versus florbetaben and PiB: a preclinical comparison study with amyloid-PET in transgenic mice

Tracer

[ 18 F]FIBT

[ 18 F]Florbetaben

[ 11 C]PiB

APP/PS1 (N = 4)

1.68 ± 0.15

1.35 ± 0.06

2.08 ± 0.24

C57BL6/J (N = 3)

0.95 ± 0.02

0.90 ± 0.01

0.99 ± 0.06

tg/ctl

1.78 ± 0.16

1.50 ± 0.06

2.11 ± 0.24

p

[18F]FIBT > [18F]florbetaben*

[11C]PiB > [18F]florbetaben*

[11C]PiB > [18F]FIBT

  1. The last row gives the statistical results of group comparisons of tg/ctl ratio values; *indicates significant difference at p < 0.05 in Bonferroni corrected t-tests.