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Table 3 Mean PET ratios (SUVR ± SD) within the four APP/PS1 tg mice and the three control mice (C57BL6/J)

From: FIBT versus florbetaben and PiB: a preclinical comparison study with amyloid-PET in transgenic mice

Tracer [ 18 F]FIBT [ 18 F]Florbetaben [ 11 C]PiB
APP/PS1 (N = 4) 1.68 ± 0.15 1.35 ± 0.06 2.08 ± 0.24
C57BL6/J (N = 3) 0.95 ± 0.02 0.90 ± 0.01 0.99 ± 0.06
tg/ctl 1.78 ± 0.16 1.50 ± 0.06 2.11 ± 0.24
p [18F]FIBT > [18F]florbetaben* [11C]PiB > [18F]florbetaben* [11C]PiB > [18F]FIBT
  1. The last row gives the statistical results of group comparisons of tg/ctl ratio values; *indicates significant difference at p < 0.05 in Bonferroni corrected t-tests.