Comparison of 4′-[methyl-11C]thiothymidine (11C-4DST) and 3′-deoxy-3′-[18F]fluorothymidine (18F-FLT) PET/CT in human brain glioma imaging

EJNMMI Research

Table 1 Patient characteristics and PET data

Case no.	Age (years)/sex	Tumor type ^a	Primary/recurrence	Ki-67 index	4DST		FLT
Case no.	Age (years)/sex	Tumor type ^a	Primary/recurrence	Ki-67 index	SUVmax	T/N ratio	SUVmax	T/N ratio
1	64/F	DA	Primary	1	0.53	1.71	0.57	2.71
2	22/M	DA	Primary	5	0.53	1.51	0.28	1.75
3	46/M	AA	Primary	15	0.85	2.24	0.95	5.59
4	73/M	AA	Primary	20	2.35	6.91	2.41	14.18
5	64/M	AOA	Primary	85	1.13	3.77	1.06	7.57
6	69/F	GBM	Primary	20	1.63	4.66	1.34	6.70
7	39/F	GBM	Primary	70	1.44	4.80	1.72	7.82
8	76/F	GBM	Primary	90	6.95	18.29	3.23	17.95
9	72/F	GBM-O	Primary	70	1.57	4.76	1.35	7.11
10	34/M	AA	Recurrence	22	2.24	9.33	1.88	14.46
11	73/M	AOA	Recurrence	80	2.67	8.34	4.68	20.35
12	47/F	AOA	Recurrence	35	1.52	4.34	1.78	7.74
13	52/M	GBM	Recurrence	15	2.80	6.09	2.56	15.06
14	46/M	GBM	Recurrence	35	3.50	10.94	3.52	15.30
15	29/F	GBM	Recurrence	50	1.56	6.50	1.52	13.82
16	46/M	GBM	Recurrence	70	3.11	8.64	3.12	18.35
17	29/F	GBM	Recurrence	60	1.22	4.69	1.95	13.93
16	79/F	GBM	Recurrence	40	1.90	4.63	1.94	7.46
19	69/M	GBM	Recurrence	5	1.52	4.47	1.45	8.06
20	29/F	GBM-O	Recurrence	20	1.10	2.50	1.38	5.11

^aDA: diffuse astrocytoma, AA: anaplastic astrocytoma, AOA: anaplastic oligoastrocytoma, GBM: glioblastoma, GBM-O: glioblastoma with oligodendroglioma component. 4DST: 4′-thiothymidine, FLT: fluorothymidine, SUVmax: maximum standardized uptake value, T/N ratio: tumor-to-normal tissue uptake ratio.