Figure 3
Linear regression analysis between the Ki-67 labeling index and the uptake values of 11 C-4DST and 18 F-FLT. (A) A significant correlation is observed between the Ki-67 labeling index in the tumor and the SUVmax of 11C-4DST (r = 0.46, P < 0.05) and 18F-FLT (r = 0.49, P < 0.05). (B) A significant correlation is also observed between the Ki-67 labeling index in the tumor and the T/N ratio of 11C-4DST (r = 0.50, P < 0.05) and 18F-FLT (r = 0.50, P < 0.05). (C) A significant correlation is also observed between the Ki-67 labeling index in the tumor and the T/B ratio of 11C-4DST (r = 0.52, P < 0.05) and 18F-FLT (r = 0.55, P < 0.05). 18F-FLT, 3′-deoxy-3′-[18F]fluorothymidine; 11C-4DST, 4′-[methyl-11C]thiothymidine; SUVmax, maximum standardized uptake value; T/N ratio, tumor-to-normal tissue uptake ratio; T/B ratio, tumor-to-blood uptake ratio.