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Figure 2 | EJNMMI Research

Figure 2

From: Comparison of 4′-[methyl-11C]thiothymidine (11C-4DST) and 3′-deoxy-3′-[18F]fluorothymidine (18F-FLT) PET/CT in human brain glioma imaging

Figure 2

Gd-enhanced T1-weighted MRI, 11 C-4DST PET, and 18 F-FLT PET of two patients. (A) A 76-year-old woman with newly diagnosed glioblastoma (Case 8). Gd-enhanced T1-weighted MR image demonstrates a round lesion with irregular ring enhancement in the right frontal lobe. PET studies with 11C-4DST and 18F-FLT PET show almost identical tracer uptake in the tumor. Background uptake of 11C-4DST is higher than 18F-FLT PET. (B) A 29-year-old woman with recurrent glioblastoma with oligodendroglioma component (Case 20). Gd-enhanced T1-weighted MR image demonstrates multiple spotty enhancements in the right temporo-occipital lobes extending to the basal ganglia. The tumor is faintly visualized with 11C-4DST but well visualized with 18F-FLT. 18F-FLT, 3′-deoxy-3′-[18F]fluorothymidine; 11C-4DST, 4′-[methyl-11C]thiothymidine.

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