Figure 3
TACs representing NSCLC tumor kinetics following injection of [ 11 C]erlotinib. Tumor TACs were obtained after i.v. injection of [11C]erlotinib into NSCLC tumor-bearing mice, demonstrating increased radioactivity uptake in erlotinib-sensitive tumors (HCC827 and NCI-H3255) compared to insensitive (QG56) or resistant (NCI-H1975) ones. The number of scanned tumors is indicated in brackets. **p < 0.01 and ***p < 0.001.