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Figure 1 | EJNMMI Research

Figure 1

From: Transcriptional response in normal mouse tissues after i.v. 211At administration - response related to absorbed dose, dose rate, and time

Figure 1

Workflow diagram for overview on treatment and sampling. Female BALB/c nude mice were intravenously injected with 1.7 kBq 211At and killed after 1 h, 6 h, and 7 days or injected with 105 or 7.5 kBq 211At and killed after 1 and 6 h, respectively. The kidneys, liver, lungs, and spleen were excised, frozen and stored. Kidney cortex and kidney medulla were dissected and treated separately. Total RNA was extracted from tissue samples and subjected to microarray analysis. For details on data processing and analysis, please refer to text.

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