Table 3 MBFi ( K ₁ ), MVO ₂ ( k ₂ ), and RPP responses to NE- and SB-stress

Normal

NE 3.2

1.68 ± 0.42

1.58 ± 0.28

0.99 ± 0.29

1.19 ± 0.10

1.39 ± 0.35 (25%)

SB 0.2

1.39 ± 0.27

1.37 ± 0.15

1.00 ± 0.10

1.00 ± 0.02*

1.39 ± 0.27 (19%)

SB 1.0

1.75 ± 0.25***

1.73 ± 0.23***

1.00 ± 0.14

0.98 ± 0.02*

1.78 ± 0.25*** (14%)

PHE + NE 3.2

1.61 ± 0.51

1.95 ± 0.45

1.27 ± 0.35

0.89 ± 0.15*

1.81 ± 0.57 (32%)

eNOS knockout

NE 3.2

1.12 ± 0.23*

1.57 ± 0.34

1.46 ± 0.50

1.13 ± 0.04

0.99 ± 0.20* (20%)

NOS inhibition

NE 3.2

1.03 ± 0.23*

1.35 ± 0.20

1.35 ± 0.29

1.07 ± 0.02*

0.96 ± 0.22* (23%)

SB 0.2

0.99 ± 0.15*^,**

1.17 ± 0.08*^,**

1.20 ± 0.12**

1.00 ± 0.03*

0.98 ± 0.15*^,** (15%)

SB 1.0

1.38 ± 0.17**^,***

1.58 ± 0.37***

1.16 ± 0.29

0.99 ± 0.02*

1.39 ± 0.17**^,*** (12%)