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Figure 5 | EJNMMI Research

Figure 5

From: β2-adrenergic stress evaluation of coronary endothelial-dependent vasodilator function in mice using 11C-acetate micro-PET imaging of myocardial blood flow and oxidative metabolism

Figure 5

Flow reserve response to β-adrenergic vasodilator stressors, NOS inhibition, and eNOS knockout. NE norepinephrine 3.2 μg/kg/min, SB High salbutamol 1.0 μg/kg/min, SB Low salbutamol 0.2 μg/kg/min. High-dose SB flow reserve is the sum of NO-mediated endothelial (EFRNOM) and non-NO-mediated microvascular flow responses. NE-stress (green), SB-stress (blue). *p < 0.05 NOS inhibition vs. same stressor without NOS inhibition.

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