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Figure 6 | EJNMMI Research

Figure 6

From: An evaluation of the brain distribution of [11C]GSK1034702, a muscarinic-1 (M1) positive allosteric modulator in the living human brain using positron emission tomography

Figure 6

Predicted time course of GSK1034702 concentration in the human brain following a single 5-mg oral dose in subject 4. Regions of interest: MTL = medial temporal lobe (defined above), WM = all cerebral white matter, cortex = sum of cortical regions (including grey and white matter), plasma = the measured plasma concentration of GSK1034702 for comparison.

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