Figure 5From: Synthesis and preclinical evaluation of DOTAGA-conjugated PSMA ligands for functional imaging and endoradiotherapy of prostate cancerCell binding and internalization kinetics of177Lu- 10 and177Lu-11 in LNCaP cells. In PLL-coated plates, 125,000 cells/well were incubated with the respective radioligand (c = 0.5 nM) at 37°C in DMEM-F12 (5% BSA). The total cellular activity was corrected for non-specific binding (10 μM PMPA). All data are expressed as mean ± SD (n = 3).Back to article page