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Figure 2 | EJNMMI Research

Figure 2

From: Evaluation of retinol binding protein 4 and carbamoylated haemoglobin as potential renal toxicity biomarkers in adult mice treated with 177Lu-octreotate

Figure 2

Analysis of urinary RBP4. Mean differences between the log10-transformed mean values (from three consecutive days) and the log10-transformed baseline mean values (from three consecutive days) for (A) creatinine and (B) RBP4 and (C) RBP4/creatinine, in non-treated mice (blue circle, n = 4 to 6), and in mice treated with 60 MBq (red square, n = 5 to 6) or 120 MBq 177Lu-octreotate (green diamond, n = 5 to 6) vs. time after study start. Log10-transformation was done since the values are skewed (see `Methods'). All values are shown as mean ± SEM. Upward arrows indicate that the mean RBP4 value is higher and downward arrows that it is lower than presented (see text). The heavy asterisk indicates data statistically significant different from baseline (p <0.05).

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