Agonist signalling properties of radiotracers used for imaging of dopamine D2/3 receptors

EJNMMI Research

Table 1 Radioligand binding and functional activities of different compounds*

*pKi, pEC₅₀ and E_max values are the average of at least two duplicate experiments with standard deviations (SD) values that were less than a third of the mean.
^¿Parts published earlier in van Wieringen et al, 2014 [19].
^¿For IBZM no high-affinity state was detected; pK_i value represents affinity for the total number of D₂ receptors.