EJNMMI Research

Table 1 Tissue-to-blood (Ti/B) ratios of ¹¹¹ In-DTPA-11B6 in NMRI nude mice carrying LNCaP xenografts

From: Preclinical imaging of kallikrein-related peptidase 2 (hK2) in prostate cancer with a ¹¹¹In-radiolabelled monoclonal antibody, 11B6

	4 h	24 h	48 h	72 h	168 h
Tumour	0.23 ± 0.10	0.80 ± 0.12	1.6 ± 0.41	1.7 ± 0.44	2.4 ± 0.62
Heart	0.23 ± 0.02	0.26 ± 0.03	0.26 ± 0.03	0.24 ± 0.02	0.22 ± 0.16
Lung	0.33 ± 0.12	0.36 ± 0.07	0.48 ± 0.12	0.43 ± 0.07	0.47 ± 0.05
Liver	0.28 ± 0.04	0.36 ± 0.02	0.43 ± 0.03	0.44 ± 0.04	0.55 ± 0.14
Spleen	0.23 ± 0.06	0.34 ± 0.09	0.50 ± 0.09	0.49 ± 0.07	0.64 ± 0.06
GI tract	0.07 ± 0.004	0.08 ± 0.003	0.09 ± 0.01	0.11 ± 0.04	0.08 ± 0.01
Kidneys	0.35 ± 0.05	0.40 ± 0.03	0.41 ± 0.05	0.37 ± 0.04	0.35 ± 0.03
Salivary	0.10 ± 0.01	0.44 ± 0.08	0.86 ± 0.11	1.3 ± 0.11	2.1 ± 0.38
Muscle	0.02 ± 0.003	0.08 ± 0.03	0.09 ± 0.05	0.09 ± 0.02	0.06 ± 0.01
Bone	0.07 ± 0.03	0.12 ± 0.01	0.34 ± 0.34	0.17 ± 0.05	0.27 ± 0.07
Brain	0.02 ± 0.003	0.02 ± 0.003	0.02 ± 0.003	0.02 ± 0.001	0.02 ± 0.003
Prostate	0.06 ± 0.01	0.24 ± 0.04	0.14 ± 0.04	0.19 ± 0.04	0.20 ± 0.05
Testes	0.12 ± 0.02	0.16 ± 0.02	0.15 ± 0.02	0.17 ± 0.02	0.27 ± 0.20

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