The effect of volume of interest definition on quantification of lymph node immune response to a monkeypox virus infection assessed by 18F-FDG-PET

EJNMMI Research

Table 1 Repeatability of ¹⁸ F-FDG SUV measurements in the LN of normal rhesus macaques using SUVs with different VOI metrics

SUV method scan pair comparison	Mean difference ± SD	95% limits of agreement: lower limit, upper limit	Coefficient of repeatability
SUV_{fixed volume}
Scans 1 and 2	-0.40 ± 1.84	-4.01, 3.20	3.60
Scans 1 and 3	0.16 ± 1.74	-3.25, 3.57	3.41
Scans 2 and 3	0.57 ± 1.18	-1.75, 2.88	2.31
mSUV_threshold
Scans 1 and 2	-0.89 ± 1.42	-3.68, 1.90	2.79
Scans 1 and 3	-0.41 ± 0.92	-2.21, 1.39	1.80
Scans 2 and 3	0.22 ± 1.94	-3.59, 4.03	3.81
SUV_threshold
Scans 1 and 2	-0.28 ± 0.89	-2.02, 1.46	1.74
Scans 1 and 3	-0.21 ± 0.50	-1.19, 0.78	0.99
Scans 2 and 3	0.19 ± 1.26	-2.28, 2.65	2.47
SUV_mean
Scans 1 and 2	0.004 ± 1.08	-2.12, 2.19	2.12
Scans 1 and 3	0.15 ± 0.72	-1.26, 1.56	1.41
Scans 2 and 3	0.12 ± 0.78	-1.41, 1.64	1.52
SUV_max
Scans 1 and 2	-1.61 ± 3.01	-7.52, 4.29	5.91
Scans 1 and 3	0.004 ± 1.82	-3.52, 3.53	3.53
Scans 2 and 3	1.65 ± 3.51	-5.23, 8.54	6.88