Skip to main content

Table 5 Mean absorbed doses per administered activity for 90 Y, 111 In, 177 Lu and 213 Bi (including daughters) labelled to 0.03 nmol PP-F11

From: Therapeutic application of CCK2R-targeting PP-F11: influence of particle range, activity and peptide amount

Mass (mg)

Absorbed dose per administered activity (mGy/MBq)

90Y

111In

177Lu

213Bi + daughters

1-Exp

2-Exp

1-Exp

2-Exp

1-Exp

2-Exp

1-Exp

2-Exp

1

40

143

12

45

46

259

492

503

5

68

242

14

50

53

299

508

519

10

85

302

14

52

56

311

514

525

50

139

493

15

54

59

332

524

536

100

168

597

15

55

60

338

527

539

200

199

708

15

57

61

343

530

542

300

217

773

16

57

62

345

532

544

500

240

853

16

59

62

348

533

545

  1. Tumour spheres vary in mass between 1 and 500 mg. Single-exponential (1-Exp) clearance proceeds with T1/2 = 4.8 h and double-exponential (2-Exp) clearance with T1/2 = 2.7 h (60%) and 150 h (40%).