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Table 5 Mean absorbed doses per administered activity for 90 Y, 111 In, 177 Lu and 213 Bi (including daughters) labelled to 0.03 nmol PP-F11

From: Therapeutic application of CCK2R-targeting PP-F11: influence of particle range, activity and peptide amount

Mass (mg) Absorbed dose per administered activity (mGy/MBq)
90Y 111In 177Lu 213Bi + daughters
1-Exp 2-Exp 1-Exp 2-Exp 1-Exp 2-Exp 1-Exp 2-Exp
1 40 143 12 45 46 259 492 503
5 68 242 14 50 53 299 508 519
10 85 302 14 52 56 311 514 525
50 139 493 15 54 59 332 524 536
100 168 597 15 55 60 338 527 539
200 199 708 15 57 61 343 530 542
300 217 773 16 57 62 345 532 544
500 240 853 16 59 62 348 533 545
  1. Tumour spheres vary in mass between 1 and 500 mg. Single-exponential (1-Exp) clearance proceeds with T1/2 = 4.8 h and double-exponential (2-Exp) clearance with T1/2 = 2.7 h (60%) and 150 h (40%).