Skip to main content

Table 4 Tumour time-integrated activity coefficients (TIAC) per mass for 90 Y, 111 In, 177 Lu and 213 Bi with its daughters

From: Therapeutic application of CCK2R-targeting PP-F11: influence of particle range, activity and peptide amount

Kinetics TIAC per tumour mass [in s/g]
90Y 111In 177Lu 213Bi 213Po 209Pb 209Tl
1 − Exponential 261 262 272 380 372 228 8
+ Fast uptake 258 259 269 361 353 230 8
+ Slow uptake 245 246 256 309 303 238 7
2 − Exponential 928 956 1,523 388 380 256 8
  1. The clearance kinetics was modeled by a single-exponential (1-Exp) or by double (2-Exp) clearance (see Figure 1B,C). The uptake kinetics in the case of single-exponential clearance was either instantaneous (1-Exp) or according to the fast or slow uptake curves indicated in Figure 1B. All values are for a peptide amount of 0.03 nmol PP-F11.