EJNMMI Research

Table 4 Tumour time-integrated activity coefficients (TIAC) per mass for ⁹⁰ Y, ¹¹¹ In, ¹⁷⁷ Lu and ²¹³ Bi with its daughters

From: Therapeutic application of CCK2R-targeting PP-F11: influence of particle range, activity and peptide amount

Kinetics	TIAC per tumour mass [in s/g]
Kinetics	⁹⁰Y	¹¹¹In	¹⁷⁷Lu	²¹³Bi	²¹³Po	²⁰⁹Pb	²⁰⁹Tl
1 − Exponential	261	262	272	380	372	228	8
+ Fast uptake	258	259	269	361	353	230	8
+ Slow uptake	245	246	256	309	303	238	7
2 − Exponential	928	956	1,523	388	380	256	8

The clearance kinetics was modeled by a single-exponential (1-Exp) or by double (2-Exp) clearance (see Figure 1B,C). The uptake kinetics in the case of single-exponential clearance was either instantaneous (1-Exp) or according to the fast or slow uptake curves indicated in Figure 1B. All values are for a peptide amount of 0.03 nmol PP-F11.

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