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Table 2 Biochemical parameters at baseline, 4 h and 24 h after the beginning of amino acid (AA) infusion

From: Influence of the amount of co-infused amino acids on post-therapeutic potassium levels in peptide receptor radionuclide therapy

 

Normal range

Baseline (75 g AA)

Baseline (50 g AA)

pvalue (baseline 75 g vs. 50 g AA)

4 h post-infusion (75 g AA)

4 h post-infusion (50 g AA)

pvalue (4 h post-infusion 75 g vs. 50 g AA)

24 h post-infusion (75 g AA)

24 h post-infusion (50 g AA)

pvalue (24 h post-infusion 75 g vs. 50 g AA)

Potassium (mmol/l)

3.5-5

4.4?±?0.4

4.3?±?0.42

0.491

5.8?±?0.7

5.7?±?0.8

0.338

4.5?±?0.4

4.6?±?0.4

0.243

GFR (ml/min)

>60

89.5?±?27.1

89.4?±?24.6

0.862

85.3?±?24.8

84.0?±?26.2

0.324

84.6?±?26.2

93.2?±?26.9

0.011

Creatinine (mg/dl)

<0.95

0.89?±?0.27

0.85?±?0.28

0.444

0.92?±?0.24

0.91?±?0.26

0.952

0.93?±?0.25

0.83?±?0.19

0.016

BUN (mg/dl)

10-50

33.28?±?12.86

30.91?±?14.16

0.808

41.88?±?12.23

40.2?±?14.06

0.872

35.62?±?13.81

34.7?±?22.16

0.099

Phosphate (mmol/l)

0.87-1.45

1.08?±?0.19

1.06?±?0.17

0.601

0.85?±?0.16

0.96?±?0.16

0.167

1.16?±?0.25

1.15?±?0.24

0.074

Chloride (mmol/l)

94-110

99.00?±?2.00

109.44?±?27.95

0.180

106.00?±?4.59

109.13?±?2.29

0.102

103.55?±?5.24

107.15?±?2.67

0.157

LDH (U/l)

<250

216.65?±?66.11

205.04?±?57.65

0.811

223.41?±?55.08

257.18?±?128.22

0.953

217.2?±?52.58

247.69?±?82.70

0.674

  1. Values are means?±?SD. GFR glomerular filtration rate, BUN blood urea nitrogen, LDH lactate dehydrogenase, mmol/l millimoles per litre, ml/min millilitres per minute, mg/dl milligrams per decilitre, U/l units per litre. Values in italics denote significant difference.