Figure 2

Histological-analysis. (a) Staphylococcus epidermidis group, van Gieson stain. Inflammatory response is expressed as a sunburst type periosteal reaction (PR) and partial resorption of the cortex (C). Implant is denoted as ‘Impl’. (b) S. epidermidis group, hematoxylin and eosin stain. Increased number of polymorphonuclear leukocytes were observed in the medullary canal in the proximity of the implant (arrow). This layer is surrounded by granulation tissue; (c) Staphylococcus aureus group, van Gieson stain; Inflammatory response is expressed as a circumferential sunburst type periosteal reaction (PR) and an almost complete resorption of the cortex (C). (d) S. aureus group, hematoxylin and eosin stain. Polymorphonuclear leukocytes are seen in the proximity of the implant (arrow). (e) Sterile catheter implant group, van Gieson stain; Periosteal and cortical reactions are absent. Reactive bone formation (RB) is seen around the implant. (f) Sterile catheter implant group, hematoxylin and eosin stain. The implant is surrounded by fibrous capsule and reactive bone (RB).