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EJNMMI Research
Figure 6 | EJNMMI Research

Figure 6

From: In vivo PET imaging of beta-amyloid deposition in mouse models of Alzheimer's disease with a high specific activity PET imaging agent [18F]flutemetamol

Figure 6

Aβ deposition in the brain of mouse models of AD. (a) Representative images show Thioflavin S staining for transgenic (TG) APP23 (27 months), Tg2576 (22 months) and APPswe-PS1dE9 (19 months) mice and wild-type (WT) control mice in the same sections used for ex vivo evaluation of [18F]flutemetamol binding in Figure 5. (b) Adjacent sections from TG APP23 (27 months), Tg2576 (22 months) and APPswe-PS1dE9 (19 months) mice and WT control mice were stained with specific anti-Aβ1-40 antibody mo, age of animal in months.

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