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Table 2 Kinetic parameters for [ 15 O]H 2 O and [ 18 F]fluciclatide at the VOI level

From: Preliminary clinical assessment of the relationship between tumor alphavbeta3 integrin and perfusion in patients studied with [18F]fluciclatide kinetics and [15O]H2O PET

Patient number K1[15O]H2O k2[15O]H2O k3/k4[18F]fluciclatide SUVfluci DELIVERY SUVfluci RETENTION
  (mL/cm3/min) (L/min) (unitless) (m2/L) (m2/L)
1 0.15 0.32 4.34 0.070 0.049
2 0.16 0.38 4.37 0.137 0.072
3 0.38 0.61 4.87 0.045 0.064
4 N/A N/A 7.81 0.050 0.087
5 N/A N/A 6.57 0.040 0.070
6 0.68 0.88 N/A N/A N/A
(Tumor#1)      
6 0.39 0.62 N/A N/A N/A
(Tumor#2)
7 0.44 0.72 4.38 0.077 0.062