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Table 1 Unlabeled drug concentrations in plasma

From: Evaluation of [11C]oseltamivir uptake into the brain during immune activation by systemic polyinosine-polycytidylic acid injection: a quantitative PET study using juvenile monkey models of viral infection

Animal Dose (mg/kg) Plasma concentration at 1 min (ng/mL) AUC (1 to 60 min) (ng/mL × min)
   Oseltamivir Ro 64-0802 Oseltamivir Ro 64-0802
  Baseline Poly I:C Baseline Poly I:C Baseline Poly I:C Baseline Poly I:C Baseline Poly I:C
M176 3.4 3.3 590 281 622 494 14,437 10,237 43,252 38,523
F175 3.0 3.0 282 222 749 727 9,291 7,782 48,849 45,976
F174 3.2 3.3 343 190 1,004 1,093 10,667 5,238 65,966 48,924
Mean 3.2 3.2 405 231 792 772 11,465 7,752 52,689 44,474
SD 0.2 0.1 163 46 195 302 2,664 2,500 11,834 5,361