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Table 2 S values for radioiodine in the human multiple thyroid models

From: Dosimetric analysis of 123I, 125I and 131I in thyroid follicle models

Source compartment r 1 r 2 Svalue Relative contributiona Relative contributionb Relative contributionc
  (μm) (μm) (Gy/Bq·s) (%) (%) (%)
123I
 Lumen 1 0 75 2.54E-07 9.6 15.0 -
 Cell layer 1 75 85 1.60E-06 27.6 - 77.3
 Cell layer 2a 85 95 2.77E-07 6.1 - 16.9
 Lumen layer 2 95 245 4.23E-08 52.7 82.0 -
 Cell layer 2b + 3a 245 265 5.86E-09 2.1 - 5.8
 Lumen layer 3 265 415 3.97E-10 1.9 2.9 -
 Cell layer 3b 415 425 7.50E-12 0.0 - 0.0
     100 100 100
125I
 Lumen 1 0 75 1.37E-07 7.7 93.6 -
 Cells layer 1 75 85 3.21E-06 82.5 - 89.9
 Cells layer 2a 85 95 2.85E-07 9.3 - 10.1
 Lumen layer 2 95 245 2.86E-10 0.5 6.4 -
 Cell layer 2b 245 255 0.00E + 00 0.0 - 0.0
     100 100 100
131I
 Lumen 1 0 75 1.03E-06 5.7 6.9 -
 Cells layer 1 75 85 1.98E-06 5.0 - 30.0
 Cells layer 2a 85 95 1.02E-06 3.3 - 19.6
 Lumen layer 2 95 245 1.44E-07 26.4 31.6 -
 Cells layer 2b + 3a 245 265 5.14E-08 2.6 - 15.8
 Lumen layer 3 265 415 2.36E-08 16.4 19.7 -
 Cells layer 3b + 4a 415 435 1.35E-08 1.9 - 11.6
 Lumen layer 4 435 585 7.68E-09 11.9 14.3 -
 Cells layer 4b + 5a 585 605 5.39E-09 1.5 - 9.0
 Lumen layer 5 605 755 3.28E-09 9.0 10.8 -
 Cells layer 5b + 6a 755 775 2.08E-09 1.0 - 5.8
 Lumen layer 6 775 925 1.31E-09 5.6 6.8 -
 Cells layer 6b + 7a 925 945 9.70E-10 0.7 - 4.0
 Lumen layer 7 945 1,095 6.81E-10 4.2 5.1 -
 Cells layer 7b + 8a 1,095 1,115 3.67E-10 0.4 - 2.1
 Lumen layer 8 1,115 1,265 3.30E-10 2.8 3.3 -
 Cells layer 8b + 9a 1,265 1,285 2.21E-10 0.3 - 1.7
 Lumen layer 9 1,285 1,435 1.12E-10 1.2 1.5 -
 Cell layer 9b 1,435 1,445 6.30E-11 0.1 - 0.3
     100 100 100
  1. The S values for the innermost follicle cell nuclei from radioiodine homogeneously distributed in the different source compartments in the human multiple thyroid follicle models (spherical compartments with r1 = inner radius and r2 = outer radius). The relative contributions to the mean absorbed dose to the innermost follicle cell nuclei from each compartment are shown for three radionuclide distributions: for 123I with two surrounding layers of follicles contributing, 125I with one surrounding layer of follicles contributing, and 131I with eight surrounding layers of follicles contributing. Follicle layers beyond these contributed with <1%. aRadioiodine homogeneously distributed within the follicle lumens and follicle cells (the entire thyroid model). bRadioiodine homogeneously distributed within the follicle lumens. cRadioiodine homogeneously distributed within the follicle cells.