Tumor concentration and quantification of sst
expression. (A) Tumor concentration of 177Lu-DOTATATE in rats receiving 177Lu-DOTATATE-only (light grey bar) and groups receiving 177Lu-DOTATATE 4 days after RAD001 therapy was started (dark grey bar). (B) Quantification of sst2 expression in primary tumors and metastases based on in vitro autoradiography. 177Lu-TATE, 177Lu-DOTA0,Tyr3-octreotate; RAD, RAD001 2.5 or 5 mg/kg; DLU, digital light unit.