Table 1 Patient information for US validation, patient information for SPECT/CT validation and retrospective US-guided injections
Parameter | Group 1, US validation (n = 10) (SD, range) | Group 2, SPECT validation (n = 34) (SD, range) | Group 3, retrospective US-guided injections (n = 21) (SD, range) |
|---|---|---|---|
Patient age (years) | 51 (8.4, 42 to 66) | 61.3 (12.1, 26 to 89) | 59 (10.6, 42 to 86) |
Tumour size (mm) | 11.5 (3.1, 9 to 20) | 17.1 (13.8, 3 to 60) | 18.4 (13.1, 8 to 55) |
Tumour type | DCIS (n = 3), IDC (n = 6), ILC (n = 1) | DCIS (n = 12), LCIS (n = 1), IDC (n = 14), ILC (n = 4), unknown (n = 3) | DCIS (n = 14), LCIS (n = 4), unknown (n = 3) |
Number of 125I seeds | 1 | with 1 seed (30), with 2 seeds (4) | 1 |
Location of 125I seeds | 3 medial, 6 lateral, 1 central | 7 medial, 22 lateral, 5 central | 5 medial, 13 lateral, 3 central |
Days after 125I seed implantation | 30 (13, 12 to 56) | 33.5 (23.3, 10 to 118) | Not measured |
125I seed depth by US (mm) | 11.6 (6.4, 5 to 23) | Not measured | Not measured |
125I seed depth by freehand SPECT (mm) | 11.5 (6.6, 5 to 25) | 15.3 (6.7, 8 to 35) | Not measured |
Difference in localisation or location (mm) | Mean difference, 0.05 (2.4, −3.5 to 5) | ||
Absolute mean difference, 1.6 (1.6, 0 to 5) | 10.9 (6.8, 0 to 29) (CT compared with SPECT) | 9.7 (6.5, 2 to 30) (CT compared with SPECT) | |
Irradical procedures | 1/10 (focal irradical) | 9/34 (focal irradical or irradical) | 5/21 (focal irradical or irradical) |