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Table 2 CT-perfusion parameters by TNM status (seventh edition)

From: Multiparametric PET/CT-perfusion does not add significant additional information for initial staging in lung cancer compared with standard PET/CT

CT-perfusion parameters T status N status M status
All tumors ( n = 46) T1 ( n = 5) T2 ( n = 29) T3 (n = 6) T4 (n = 6) p N0 ( n = 15) N1 ( n = 10) N2 (n = 9) N3 (n = 12) p M0 ( n = 28) M1 (n = 18) p
 Blood flow (mL/100 mL min-1), mean ± SD 32.1 ± 12.7 38.2 ± 28.3 28.3 ± 10.9 32.3 ± 9.5 0.81 45.6 ± 36.2 27.1 ± 10.9 35.7 ± 9.2 29.7 ± 13.9 0.14 37.6 ± 28.4 32.2 ± 12.9 0.92
 Blood volume (mL/100 mL), mean ± SD 5.6 ± 3.1 9.4 ± 7.3 6.0 ± 4.5 8.4 ± 4.4 0.26 11.3 ± 8.9 4.7 ± 2.8 10.5 ± 4.9 6.3 ± 2.7 0.005 8.4 ± 7.0 8.4 ± 5.4 0.73
 Mean transit time (s), mean ± SD 14.4 ± 2.6 13.6 ± 4.8 14.8 ± 4.2 15.9 ± 5.1 0.78 13.5 ± 5.9 14.7 ± 2.9 15.0 ± 4.2 13.9 ± 4.2 0.48 13.5 ± 4.7 15.2 ± 4.1 0.39
NSCLC ( n =41) T1 ( n  = 4) T2 ( n  = 27) T3 ( n  = 5) T4 ( n  = 5) p N0 ( n  = 14) N1 ( n  = 10) N2 ( n  = 6) N3 ( n  = 11) p M0 ( n  = 26) M1 ( n  = 15) p
 Blood flow (mL/100 mL min-1), mean ± SD 32.0 ± 14.7 38.2 ± 29.3 30.6 ± 10.4 28.3 ± 10.9 0.96 47.7 ± 36.7 27.1 ± 10.9 34.9 ± 9.2 27.9 ± 13.1 0.08 37.4 ± 29.4 32.2 ± 12.7 0.89
 Blood volume (mL/100 mL), mean ± SD 6.0 ± 3.5 9.5 ± 7.5 6.2 ± 4.9 6.0 ± 4.5 0.57 11.9 ± 9.0 4.7 ± 2.8 10.4 ± 4.6 6.2 ± 2.8 0.003 8.6 ± 7.2 8.0 ± 5.3 0.95
 Mean transit time (s), mean ± SD 13.8 ± 2.6 13.8 ± 4.7 15.5 ± 4.3 16.6 ± 5.4 0.65 13.6 ± 6.1 14.7 ± 2.9 15.1 ± 5.1 14.7 ± 3.6 0.62 13.7 ± 4.6 15.6 ± 4.3 0.30
  1. CT, computed tomography; NSCLC, non-small cell lung carcinoma; SD, standard deviation.