Patient with peripheral adenocarcinoma of the left lower lobe. (A) Coronal PET-MIP, (B) axial PET, (C) axial CT in lung window, and (D) axial 18F-FDG-PET/CT co-registration. The green VOI encompasses the metabolic tumor volume with 42% isocontour. The tumor is 34.7 mm in size and exhibits a SUVmax of 7.1, SUVmean of 4.6, TLG of 54.9, and PETvol of 11.8 cm3. (E) Axial time MIP. Color-coded maps for (F) BF, (G) BV, and (H) MTT. The tumor has a BF of 29.8 mL/100 mL min-1, a BV of 7.1 mL/100 mL, and an MTT of 12.2 s. (I) MVD analysis of the post-surgical specimen stained in hematoxylin/eosin, detected vessels labelled blue. 18F-FDG-PET/CT, 18F-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography; BF, blood flow; BV, blood volume; CT, computed tomography; MVD, microvessel density; MTT, mean transit time; MIP, maximum intensity projection; PET, positron emission tomography; PETvol, metabolic tumor volume; SUVmax, maximum standardized uptake value; SUVmean, mean standardized uptake value; TLG, total lesion glycolysis; VOI, volume of interest.