Figure 4
MMTV-PyMT mouse scanned after injection with ( R )-[11C]PAQ followed by [18 F]FDG 100 min later and MRI after euthanasia. (R)-[11C]PAQ and [18 F]FDG images are summed over 60 and 40 min, respectively. Tumour areas are outlined with orange, and in (C2) and (D2) the lungs with green lines. (A) Areas with the highest [18 F]FDG uptake are shown as a white overlay over the MRI image. (B) (R)-[11C]PAQ images fused with the MRI image. The green lines drawn over (A) and (B) indicate the position of each transaxial image. (C1-C3) Transaxial images of the mouse with fused [18 F]FDG, (R)-[11C]PAQ and MRI images. (D1-D3) Areas of interest magnified, illustrating discrepancies in the uptake of the two tracers.