Figure 9

Thyroid uptake of ¹²³I-CMICE-013 versus two other perfusion agents. The thyroid uptake values (%ID/organ) of two 7'(Z)-¹²⁵I-iodorotenol and 7′(Z)-¹²⁵I-iodorotenone were compared to ¹²³I-CMICE-013 at 1, 2, and 24 h post-injection. A 102-min data of ¹²³I-CMICE-013 was used as 2-h data in this graph. All data were expressed as mean ± SD. The number of animals at each time point (in the order of 1, 2, 24 h) is ¹²³I-CMICE-013 n = 6, 6, 8; 7'(Z)-¹²⁵I-iodorotenol n = 3, 4, 4; 7'(Z)-¹²⁵I-iodorotenone n = 7, 6, 4. * P < 0.05, ** P < 0.001, *** P < 0.0001 versus ¹²³I-CMICE-013 at the same time point.