Table 1 Time taken to reach 50% LE of four His-tagged proteins at varying [Na+]
From: Optimising the radiolabelling properties of technetium tricarbonyl and His-tagged proteins
His-tagged protein | 0.25 M [Na+] | 0.44 M [Na+] | 0.63 M [Na+] |
|---|---|---|---|
rCR2 | - | 34 ± 1.4 min | 10.2 ± 0.1 min |
α-CD33 scFv | 58.5 ± 6.3 min | 31.7 ± 3.5 min | 19.5 ± 2.4 min |
α-PMSA scFv | 15.2 ± 3.8 min | 4.7 ± 0.8 min | 3.9 ± 0.5 min |
α-VCAM-1 scFv | 65.5 ± 10.5 min | 19.9 ± 0.2 min | 13.2 ± 2.6 min |