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Figure 2 | EJNMMI Research

Figure 2

From: Design and preclinical evaluation of a 99mTc-labelled diabody of mAb J591 for SPECT imaging of prostate-specific membrane antigen (PSMA)

Figure 2

Ex vivo verification of PSMA expression in DU145-PSMA and DU145 tumours. Immunofluorescence staining of tumour cryo-sections was performed using J591Cdia-AlexaFluor-488 (green). Nuclei are counterstained with DAPI (blue). Three representative tumour sections are shown. All analysed DU145-PSMA sections showed strong, heterogeneous staining for PSMA. No staining was observed in DU145 tumour sections.

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