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Table 2 Results of 4DST and FDG-PET/CT for N staging in 27 patients with NSCLC who underwent lymph node resection

From: A pilot study of 4′-[methyl-11C]-thiothymidine PET/CT for detection of regional lymph node metastasis in non-small cell lung cancer

Subject

PET/CT

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

Accuracy (%)

Per-nodal station

4DST

82.4 (0.64 to 1.00)

71.7 (0.63 to 0.80)

31.8 (0.18 to 0.46)

96.2 (0.92 to 1.00)

73.2 (0.65 to 0.81)

FDG

29.4 (0.08 to 0.51)

85.8 (0.79 to 0.93)

25.0 (0.06 to 0.44)

88.3 (0.82 to 0.95)

78.0 (0.71 to 0.85)

Per-patient

4DST

66.7 (0.36 to 0.98)

33.3 (0.12 to 0.55)

33.3 (0.16 to 0.51)

66.7 (0.36 to 0.98)

44.4 (0.26 to 0.63)

FDG

22.2 (−0.05 to 0.49)

61.1 (0.39 to 0.84)

22.2 (−0.05 to 0.49)

61.1 (0.39 to 0.84)

48.1 (0.29 to 0.67)

  1. The numbers in parentheses represent 95% confidence interval; NSCLC, non-small cell lung cancer; PPV, positive predictive value; and NPV, negative predictive value.