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Table 2 Results of 4DST and FDG-PET/CT for N staging in 27 patients with NSCLC who underwent lymph node resection

From: A pilot study of 4′-[methyl-11C]-thiothymidine PET/CT for detection of regional lymph node metastasis in non-small cell lung cancer

Subject PET/CT Sensitivity (%) Specificity (%) PPV (%) NPV (%) Accuracy (%)
Per-nodal station 4DST 82.4 (0.64 to 1.00) 71.7 (0.63 to 0.80) 31.8 (0.18 to 0.46) 96.2 (0.92 to 1.00) 73.2 (0.65 to 0.81)
FDG 29.4 (0.08 to 0.51) 85.8 (0.79 to 0.93) 25.0 (0.06 to 0.44) 88.3 (0.82 to 0.95) 78.0 (0.71 to 0.85)
Per-patient 4DST 66.7 (0.36 to 0.98) 33.3 (0.12 to 0.55) 33.3 (0.16 to 0.51) 66.7 (0.36 to 0.98) 44.4 (0.26 to 0.63)
FDG 22.2 (−0.05 to 0.49) 61.1 (0.39 to 0.84) 22.2 (−0.05 to 0.49) 61.1 (0.39 to 0.84) 48.1 (0.29 to 0.67)
  1. The numbers in parentheses represent 95% confidence interval; NSCLC, non-small cell lung cancer; PPV, positive predictive value; and NPV, negative predictive value.