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Table 1 SUV parameters of 68 Ga-DOTATOC PET imaging before and directly after administration of PRRT with 7.4 GBq 177 Lu-octreotate

From: Does PRRT with standard activities of 177Lu-octreotate really achieve relevant somatostatin receptor saturation in target tumor lesions?: insights from intra-therapeutic receptor imaging in patients with metastatic gastroenteropancreatic neuroendocrine tumors

  SUV max(mean ± SD) p value a
  Pretreatment Intra-therapeutic
Tumor lesions 22.5 ± 8.5 20.0 ± 10.4 0.226
Normal liver 8.5 ± 2.5 4.8 ± 2.0 0.016
Spleen 21.4 ± 8.9 5.6 ± 0.8 0.015
SUV ratio    
  Tumor-to-liver 2.8 ± 1.3 4.7 ± 3.0 <0.001
  Tumor-to-spleen 1.2 ± 0.7 3.5 ± 1.5 <0.001
  1. aPaired t test.