Comparisons of the uptakes in tumour (a) and tumour-to-background uptake ratios (b) of 18
F-SIG343 and 18
F-SIG353. Results were presented as %ID/g in the tumour and the uptake in the tumour compared to the residual activity remained in the body (tumour-to-background uptake ratios) at 15, 30, 60 and 120 min. Data are derived from the biodistribution studies in A373 tumour-bearing mice (means ± SEM, n = 5). *P < 0.05, **P < 0.01, ***P < 0.001 treatment versus control (unpaired, two-tailed Student's t test).