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Table 2 Comparison of haemodynamic state of the brain at baseline and after 3 months between patients assigned to intervention and those to standard treatment ( n= 23)

From: Intervention versus standard medical treatment in patients with symptomatic occlusion of the internal carotid artery: a randomised oxygen-15 PET study

  Intervention n = 12 Standard n = 11 Unadjusted difference in change (95% CI) Adjusted difference in change *(95% CI)
   Mean ± SD Mean ± SD   
CBF MCA (mL/min/100 mL) Baseline 31.3 ± 5.9 33.1 ± 5.4   
3 months 31.6 ± 4.9 33.5 ± 4.7   
Change 0.34 ± 6.2 0.42 ± 4.1 −0.1 (−4.7 to 4.5) −1.0 (−7.4 to 5.4)
CBF ACA (mL/min/100 mL) Baseline 32.6 ± 5.8 35.2 ± 5.5   
3 months 32.0 ± 4.2 35.0 ± 5.7   
Change −0.56 ± 6.2 −0.28 ± 4.9 −0.3 (−5.2 to 4.6) −1.6 (−8.4 to 5.2)
CBV MCA (mL/100 mL) Baseline 3.0 ± 0.6 3.3 ± 0.9   
3 months 3.5 ± 1.4 3.2 ± 0.6   
Change 0.60 ± 1.7 −0.09 ± 1.2 0.7 (−0.6 to 2.0) 0.09 (−1.7 to 1.9)
CBV ACA (mL/100 mL) Baseline 3.0 ± 0.6 3.4 ± 1.0   
3 months 3.5 ± 1.3 3.1 ± 0.7   
Change 0.49 ± 1.6 −0.23 ± 1.3 0.7 (−0.6 to 2.0) 0.08 (−1.6 to 1.8)
OEF MCA (%) Baseline 46.4 ± 9.7 47.5 ± 5.5   
3 months 46.3 ± 7.9 48.4 ± 5.8   
Change −0.08 ± 6.1 0.85 ± 6.8 −0.9 (−6.5 to 4.7) 3.1 (−4.1 to 10.3)
OEF ACA (%) Baseline 44.4 ± 11.2 46.1 ± 6.2   
3 months 44.2 ± 7.3 47.2 ± 5.2   
  Change −0.17 ± 7.4 1.1 ± 6.3 −1.3 (−7.3 to 4.7) 3.1 (−4.6 to 10.8)
  1. Asterisk ‘*’ indicates adjusted for age and sex; measurements were performed ipsilateral to the side of the ICA occlusion; CBF, cerebral blood flow; CBV, cerebral blood volume; OEF, oxygen extraction fraction; MCA, middle cerebral artery; ACA, anterior cerebral artery.