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Table 1 Distribution volume calculated from compartmental modeling, Logan plot, MA1, and SA using regions or individual voxels

From: Kinetic analysis of [11C]befloxatone in the human brain, a selective radioligand to image monoamine oxidase A

Region V T(mL/cm 3)
Region Voxel
Unconstrained two-tissue compartment model Logan MA1 SA Logan SA
Frontal cortex 13.3 ± 0.84 (2.7) 12.5 ± 0.79 11.8 ± 0.71 13.6 ± 1.21 8.66 ± 2.14 13.7 ± 0.90
Temporal cortex 15.1 ± 1.04 (2.6) 14.1 ± 0.90 13.5 ± 0.83 15.3 ± 0.85 9.69 ± 2.64 15.4 ± 0.97
Hippocampus 16.2 ± 1.11 (6.9) 14.8 ± 1.09 13.8 ± 0.75 15.2 ± 1.74 6.36 ± 1.87 14.4 ± 1.79
Parietal cortex 13.0 ± 0.61 (2.8) 12.3 ± 0.53 11.6 ± 0.40 13.3 ± 0.94 8.59 ± 2.20 13.5 ± 1.10
Occipital cortex 15.4 ± 1.08 (2.8) 14.4 ± 0.99 13.6 ± 0.83 15.5 ± 1.20 9.87 ± 2.19 15.7 ± 1.13
Anterior cingulum 16.2 ± 1.56 (4.6) 15.2 ± 1.43 14.7 ± 1.20 16.9 ± 2.02 9.94 ± 2.56 16.2 ± 0.90
Caudate 12.5 ± 1.20 (7.7) 11.4 ± 1.00 11.0 ± 0.73 12.4 ± 1.21 7.17 ± 1.94 13.0 ± 1.36
Putamen 14.8 ± 0.67 (3.8) 13.9 ± 0.77 13.3 ± 0.70 15.2 ± 0.80 10.3 ± 3.00 16.5 ± 0.99
Thalamus 19.3 ± 1.43 (5.6) 17.7 ± 1.69 16.5 ± 1.18 19.5 ± 2.33 10.1 ± 3.11 19.0 ± 2.32
Cerebellum 6.73 ± 0.91 (2.5) 6.42 ± 0.82 6.18 ± 0.75 6.83 ± 0.95 5.19 ± 1.98 7.58 ± 0.86
  1. Values are presented as mean ± SD from seven human subjects. For each brain region, standard errors are listed in parentheses and are expressed as the percentage of the variable itself.