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EJNMMI Research
Figure 1 | EJNMMI Research

Figure 1

From: Influence of d-glutamine and d-glutamic acid sequences in optical peptide probes targeted against the cholecystokinin-2/gastrin-receptor on binding affinity, specificity and pharmacokinetic properties

Figure 1

Structural formulas of optical CCKR binding peptide probes. (a) The probes differed in the spacer sequence connecting the NIR fluorochrome DY-754 and the CCK2R binding peptide. The probe QE displayed a spacer of three negatively charged d-glutamic acids alternating with three d-glutamines. (b) The probe bivQ had a bivalent nature, where each of the two minigastrin sequences was preceded by a spacer of three d-glutamines. Structural formulas were drawn with SymyxDraw.

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