EJNMMI Research

Table 1 Proportion of simulations that had α ₀ = 0 or α ₀ ≠ 0 identified by NLSA and SA

From: Assessing radiotracer kinetics in the Langendorff perfused heart

Simulated scenario	NLSA performance						SA performance
	SNR = 60			SNR = 120			SNR = 60			SNR = 120
	α ₀ = 0 (%)	α ₀ ≠ 0 (%)	Accuracy (%)	α ₀ = 0 (%)	α ₀ ≠ 0 (%)	Accuracy (%)	α ₀ = 0 (%)	α ₀ ≠ 0 (%)	Accuracy (%)	α ₀ = 0 (%)	α ₀ ≠ 0 (%)	Accuracy (%)
Tri-exponential
No trapping (α ₀ = 0)	100	-	100	100	-	100	21	79	21	14	86	14
Trapping 1 (α ₀ = 0.006)	10	90	90	6	94	94	6	94	94	10	90	90
Trapping 2 (α ₀ = 0.06)	-	100	100	-	100	100	-	100	100	-	100	100
Trapping 3 (α ₀ = 0.2)	-	100	100	-	100	100	-	100	100	-	100	100
Trapping 4 (α ₀ = 0.6)	-	100	100	-	100	100	-	100	100	-	100	100
Bi-exponential
No trapping (α ₀ = 0)	100	-	100	100	-	100	14	86	14	2	98	2
Trapping 1 (α ₀ = 0.006)	23	77	77	13	87	87	4	96	96	-	100	100
Trapping 2 (α ₀ = 0.06)	6	94	94	2	98	98	-	100	100	-	100	100
Trapping 3 (α ₀ = 0.2)	-	100	100	-	100	100	-	100	100	-	100	100
Trapping 4 (α ₀ = 0.6)	-	100	100	-	100	100	-	100	100	-	100	100

α ₀ indicates the tracer trapping. Units are in min^-1.

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