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Table 1 Summary of animal studies

From: Assessment of three techniques for delivering stem cells to the heart using PET and MR imaging

Number Weight (g) Model Injection site No. of stem cells injected FDG activity (MBq) Notes
1 448 Infarcted Myocardium 4.4 million 0.44  
2 242 Infarcted Myocardium 4 million 0.41  
3 215 Infarcted Myocardium 6.5 million 1.78  
4 278 Infarcted Myocardium 2.3 million 0.63  
5 279 Infarcted Myocardium 5.4 million 1.70  
1 238 1 week infarcted Myocardium 6.8 million 2.22  
2 236 1 week infarcted Myocardium 6.6 million 0.41  
3 226 1 week infarcted Myocardium 5.6 million 2.60  
1 290 Infarcted Left ventricle 7 million 1.63 The animal died 1.5 h after injection
2 238 Infarcted Left ventricle 6 million 1.37 The animal died just before the start of the scan
3 203 Infarcted Left ventricle 6.6 million 2.44 Animal survived
4 233 Infarcted Left ventricle 3.7 million 1.52 Animal died before the whole-body scan
5 218 Infarcted Left ventricle 4 million 0.30 Animal died during the whole-body scan
1 226 Infarcted Femoral vein 5.4 million 2.44  
2 200 Infarcted Femoral vein 6.3 million 0.90  
3 231 Infarcted Tail vein 5.3 million 3.92  
4 260 Infarcted Tail vein 7 million 7.03  
  1. The animal models were injected with double (FDG-SPIO)-labeled ASCs via different methods of cell delivery. Each group of studies is numbered. All animals were imaged with microPET and 7-T MRI scanners. Whole-body PET data were acquired following the images of the heart at the center of field of view. The animals that died during the PET imaging (in the left ventricle injection group) were not imaged with MR.