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Figure 3 | EJNMMI Research

Figure 3

From: Concordance between in vivo and postmortem measurements of cholinergic denervation in rats using PET with [18F]FEOBV and choline acetyltransferase immunochemistry

Figure 3

Anteroposterior immunocytochemistry trend. Examples of ChAT immunocytochemistry at different anteroposterior locations. The lesioned hemisphere (left column) has a distinct loss of ChAT availability when compared with the control hemisphere (right column). Note the anteroposterior trend: highest interhemispheric differences can be observed in anterior regions such as (A) the cingulate and motor cortices (AP = +2.5 mm from the bregma), (B) with smaller differences in frontal sensorimotor regions (AP = +0.2 mm from the bregma), and (C) no quantifiable effect in the parietal cortex (AP = −2.6 mm from the bregma).

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