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Table 2 Fractional blood volume ( v b , in %) as estimated with the two-tissue compartment model

From: FDG kinetic modeling in small rodent brain PET: optimization of data acquisition and analysis

   Full TAC 50% TAC Smooth IF Smooth TAC Smooth IF and TAC
Cortex Min. χ2 a 3.8 ± 4.0 4.6 ± 3.4 3.7 ± 3.9 7.8 ± 6.2 6.3 ± 1.9
Model fitb 7.2 ± 4.0 9.7 ± 7.2 3.7 ± 3.8 15.1 ± 7.1 6.3 ± 1.8
Hypothalamus Min. χ2 12.7 ± 2.7c Not fitted Not fitted Not fitted 11.1 ± 5.0
Model fit 11.7 ± 1.1c 11.5 ± 4.1c
  1. aMin. χ2, v b was varied manually to yield the best goodness of fit (minimal χ2). bModel fit, v b was included as model parameter to be fitted. cSignificant difference to respective value for the cortex but unrealistically high.