EJNMMI Research

Table 2 Fractional blood volume ( v _b , in %) as estimated with the two-tissue compartment model

From: FDG kinetic modeling in small rodent brain PET: optimization of data acquisition and analysis

		Full TAC	50% TAC	Smooth IF	Smooth TAC	Smooth IF and TAC
Cortex	Min. χ^{2 a}	3.8 ± 4.0	4.6 ± 3.4	3.7 ± 3.9	7.8 ± 6.2	6.3 ± 1.9
Cortex	Model fit^b	7.2 ± 4.0	9.7 ± 7.2	3.7 ± 3.8	15.1 ± 7.1	6.3 ± 1.8
Hypothalamus	Min. χ²	12.7 ± 2.7^c	Not fitted	Not fitted	Not fitted	11.1 ± 5.0
Hypothalamus	Model fit	11.7 ± 1.1^c	Not fitted	Not fitted	Not fitted	11.5 ± 4.1^c

^aMin. χ², v _b was varied manually to yield the best goodness of fit (minimal χ²). ^bModel fit, v _b was included as model parameter to be fitted. ^cSignificant difference to respective value for the cortex but unrealistically high.

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