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Table 1 Literature results of two-tissue compartmental FDG kinetic modeling in small rodents

From: FDG kinetic modeling in small rodent brain PET: optimization of data acquisition and analysis

Reference K 1 k 2 k 3 k 4 K FDG(mL/min/cm 3) v b(%) CMR glc(μmol/min/100 g) Anesthesia LC Sp
Millet et al. [12] 0.14 ± 0.05 0.19 ± 0.25 0.07 ± 0.05 0.005 ± 0.004 0.044 ± 0.013 -a 90.3 ± 27.6 Urethane 0.6 R
Wu et al. [14] 0.10 ± 0.03 0.21 ± 0.10 0.05 ± 0.02 0.015 ± 0.006 0.019 ± 0.005 0 21.5 ± 4.3 Isoflurane 0.625 M
Yu et al. [15] 0.22 ± 0.05 0.48 ± 0.09 0.06 ± 0.02 0.025 ± 0.010 0.024 ± 0.007 0 40.6 ± 13.3 Isoflurane 0.6 M
Mizuma et al. [13] 0.20 ± 0.02 0.39 ± 0.05 0.14 ± 0.02 0.015 ± 0.002 0.053 ± 0.013 0 39 ± 3 Awake 0.625 M
Mizuma et al. [13] 0.156 ± 0.009 0.329 ± 0.005 0.032 ± 0.006 0.009 ± 0.004 0.014 ± 0.004 0 13 ± 4 Isoflurane 0.625 M
Alf et al. [7] 0.27 ± 0.09 0.57 ± 0.10 0.08 ± 0.02 0.018 ± 0.004 0.035 ± 0.013 5.5 61 ± 11 Isoflurane 0.6 M
  1. Units for K 1 to k 4 as in Figure 3, K FDG in [mL/min/cm3] and CMRglc in [μmol/min/100 g]. a v b included in the model. Sp, species; M, mouse; R, rat.