Skip to main content

Table 1 Literature results of two-tissue compartmental FDG kinetic modeling in small rodents

From: FDG kinetic modeling in small rodent brain PET: optimization of data acquisition and analysis

Reference

K 1

k 2

k 3

k 4

K FDG(mL/min/cm 3)

v b(%)

CMR glc(μmol/min/100 g)

Anesthesia

LC

Sp

Millet et al. [12]

0.14 ± 0.05

0.19 ± 0.25

0.07 ± 0.05

0.005 ± 0.004

0.044 ± 0.013

-a

90.3 ± 27.6

Urethane

0.6

R

Wu et al. [14]

0.10 ± 0.03

0.21 ± 0.10

0.05 ± 0.02

0.015 ± 0.006

0.019 ± 0.005

0

21.5 ± 4.3

Isoflurane

0.625

M

Yu et al. [15]

0.22 ± 0.05

0.48 ± 0.09

0.06 ± 0.02

0.025 ± 0.010

0.024 ± 0.007

0

40.6 ± 13.3

Isoflurane

0.6

M

Mizuma et al. [13]

0.20 ± 0.02

0.39 ± 0.05

0.14 ± 0.02

0.015 ± 0.002

0.053 ± 0.013

0

39 ± 3

Awake

0.625

M

Mizuma et al. [13]

0.156 ± 0.009

0.329 ± 0.005

0.032 ± 0.006

0.009 ± 0.004

0.014 ± 0.004

0

13 ± 4

Isoflurane

0.625

M

Alf et al. [7]

0.27 ± 0.09

0.57 ± 0.10

0.08 ± 0.02

0.018 ± 0.004

0.035 ± 0.013

5.5

61 ± 11

Isoflurane

0.6

M

  1. Units for K 1 to k 4 as in Figure 3, K FDG in [mL/min/cm3] and CMRglc in [μmol/min/100 g]. a v b included in the model. Sp, species; M, mouse; R, rat.