Effect of fractional blood volume on the single rate constants. K
(A) and k
(B) showed an almost linear relationship in the cortex, while the pattern for k
(C) and k
(D) was more complex. Effects were independent of the brain region. Single asterisk (*) denotes the results from model fits using smoothed data deviated significantly (P < 0.05) from those achieved with the full TAC. Error bars are omitted for better readability.