Post-radioembolization yttrium-90 PET/CT - part 2: dose-response and tumor predictive dosimetry for resin microspheres

EJNMMI Research

Table 1 Tumor ⁹⁰ Y dose-response by dose-volume histograms

Patient number	Tumor type	Tumor size (cm ³)	D ₇₀(Gy)	V ₁₀₀(%)	Mean dose (Gy)	Follow-up (months)	Response
23	HCC	≈2.4^a	≈74^a	≈47^a	≈108^a	3	Complete
8	HCC	≈4.7^a	≈101^a	≈71^a	≈168^a	2.8	Complete
23	HCC	25.0	142	80	263	3	Complete
23	HCC	36.6	122	77	215	3	Complete
21	HCC	74.4	213	91	425	5.5	Complete
23	HCC	149.3	89	65	137	3	Partial
1	HCC	1,162.3	85	64	151	1.8	Minor
2	HCC	1,414.4	37	45	105	6.7	Stable
19	HCC	3,341.1	40	28	77	12	Partial; adjuvant sorafenib
17	Cholangiocarcinoma	345.9	90	63	120	3.3	Complete
9	Adrenal GIST	399.5	53	41	121	9.5	Partial

^aSubject to partial volume effect and excluded from cross-analysis in Figure 5.