Figure 5

Intra- and inter-observer variability for different anatomical (CT) slice levels for rabbit, ferret, and mouse animals. (A,C,E) Multiple CT axial image slices from a rabbit, ferret, and mouse that have been segmented manually using a live-wire algorithm, by the same operator, in two different time points (red, time number 1, green, time number 2). (B,D,F) Rabbit and ferret segmentations from two different observers highlighted in red and green, respectively, across multiple lung locations. Intra-observer (A,C,E) and inter-observer (B,D,F) evaluations of the segmentation process show good agreement across four different lung locations. Quantitative evaluations of these processes are reported in Table 3.