EJNMMI Research

Table 1 Percentages of radioactivity after the injection of [ ¹¹ C]MMPIP in the plasma and brain

From: Synthesis and evaluation of [¹¹C]MMPIP as a potential radioligand for imaging of metabotropic glutamate 7 receptor in the brain

Post-injection (min)	Plasma			Brain
Post-injection (min)	Intact	Metabolite 1	Metabolite 2	Intact	Metabolite 1	Metabolite 2
5	81.3 ± 8.4	13.4 ± 6.0	5.3 ± 2.5	92.0 ± 2.7	1.5 ± 0.5	6.5 ± 2.5
15	48.7 ± 4.1	36.7 ± 5.8	14.6 ± 2.5	72.3 ± 3.6	8.2 ± 0.7	19.5 ± 3.0
30	30.6 ± 3.7	43.3 ± 1.2	26.1 ± 4.9	36.2 ± 2.9	23.1 ± 2.4	40.7 ± 5.2
60	18.0 ± 0.3	62.1 ± 3.9	19.9 ± 3.6	18.5 ± 3.5	47.9 ± 12.7	33.5 ± 9.2

Percentages are expressed as mean ± S.D., n = 3.

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