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Table 1 Percentages of radioactivity after the injection of [ 11 C]MMPIP in the plasma and brain

From: Synthesis and evaluation of [11C]MMPIP as a potential radioligand for imaging of metabotropic glutamate 7 receptor in the brain

Post-injection (min) Plasma Brain
Intact Metabolite 1 Metabolite 2 Intact Metabolite 1 Metabolite 2
5 81.3 ± 8.4 13.4 ± 6.0 5.3 ± 2.5 92.0 ± 2.7 1.5 ± 0.5 6.5 ± 2.5
15 48.7 ± 4.1 36.7 ± 5.8 14.6 ± 2.5 72.3 ± 3.6 8.2 ± 0.7 19.5 ± 3.0
30 30.6 ± 3.7 43.3 ± 1.2 26.1 ± 4.9 36.2 ± 2.9 23.1 ± 2.4 40.7 ± 5.2
60 18.0 ± 0.3 62.1 ± 3.9 19.9 ± 3.6 18.5 ± 3.5 47.9 ± 12.7 33.5 ± 9.2
  1. Percentages are expressed as mean ± S.D., n = 3.